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Issue 7, 2014
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Use of a new water-soluble Zn sensor to determine Zn affinity for the amyloid-β peptide and relevant mutants

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Abstract

Evaluation of Zn affinity for the amyloid-β peptide involved in Alzheimer's disease and its modified counterparts is reported. This was made possible by the use of a new water-soluble chelator, the properties of which have also been described. Changes in the peptide sequence that impact Zn affinity are briefly discussed.

Graphical abstract: Use of a new water-soluble Zn sensor to determine Zn affinity for the amyloid-β peptide and relevant mutants

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Publication details

The article was received on 17 Jan 2014, accepted on 05 Mar 2014 and first published on 06 Mar 2014


Article type: Communication
DOI: 10.1039/C4MT00016A
Citation: Metallomics, 2014,6, 1220-1222
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    Use of a new water-soluble Zn sensor to determine Zn affinity for the amyloid-β peptide and relevant mutants

    S. Noël, S. Bustos Rodriguez, S. Sayen, E. Guillon, P. Faller and C. Hureau, Metallomics, 2014, 6, 1220
    DOI: 10.1039/C4MT00016A

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