Jump to main content
Jump to site search

Issue 6, 2014
Previous Article Next Article

Microfluidic assembly of multistage porous silicon–lipid vesicles for controlled drug release

Author affiliations

Abstract

A reliable microfluidic platform for the generation of stable and monodisperse multistage drug delivery systems is reported. A glass-capillary flow-focusing droplet generation device was used to encapsulate thermally hydrocarbonized porous silicon (PSi) microparticles into the aqueous cores of double emulsion drops, yielding the formation of a multistage PSi–lipid vesicle. This composite system enables a large loading capacity for hydrophobic drugs.

Graphical abstract: Microfluidic assembly of multistage porous silicon–lipid vesicles for controlled drug release

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Nov 2013, accepted on 06 Jan 2014 and first published on 06 Jan 2014


Article type: Communication
DOI: 10.1039/C3LC51260F
Author version
available:
Download author version (PDF)
Lab Chip, 2014,14, 1083-1086
  • Open access: Creative Commons BY-NC license
  •   Request permissions

    Microfluidic assembly of multistage porous silicon–lipid vesicles for controlled drug release

    B. Herranz-Blanco, L. R. Arriaga, E. Mäkilä, A. Correia, N. Shrestha, S. Mirza, D. A. Weitz, J. Salonen, J. Hirvonen and H. A. Santos, Lab Chip, 2014, 14, 1083
    DOI: 10.1039/C3LC51260F

    This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements