Jump to main content
Jump to site search

Issue 4, 2014
Previous Article Next Article

Phytochemistry and biological activity of Spanish Citrus fruits

Author affiliations


The evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase by Citrus spp. fruits of Spanish origin (lemon, orange, grapefruit, lime, and mandarin) together with the evaluation of their phytochemical content and antioxidant capacity (DPPH˙, ORACFL, ABTS+, FRAP and O2˙) aiming for new applications of the fruits in nutrition and health was carried out. As far as we are aware, the presence of 3-O-caffeoylferuoylquinic acid and two hydrated feruloylquinic acids in orange and the presence of 3,5-diferuoylquinic acid in grapefruit have been reported for the first time. Although grapefruit showed higher contents of phytochemicals such as flavanones and vitamin C, lemon and lime showed higher potential for inhibitory effects on lipase, and lime also showed the best results for in vitro α-glucosidase inhibition. On the other hand, higher antioxidant capacity was reported for grapefruit, lemon and lime, which correlated well with their phytochemical composition. Based on the results, it could be concluded that Citrus fruits are of great value for nutrition and treatment of diet-related diseases such as obesity and diabetes, and consequently, a new field of interest in the food industry regarding new bioactive ingredients would be considered.

Graphical abstract: Phytochemistry and biological activity of Spanish Citrus fruits

Back to tab navigation

Article information

21 Dec 2013
12 Jan 2014
First published
13 Jan 2014

Food Funct., 2014,5, 764-772
Article type
Author version available

Phytochemistry and biological activity of Spanish Citrus fruits

A. Gironés-Vilaplana, D. A. Moreno and C. García-Viguera, Food Funct., 2014, 5, 764
DOI: 10.1039/C3FO60700C

Social activity

Search articles by author