Water-soluble fullerene materials for bioapplications: photoinduced reactive oxygen species generation
The photoinduced reactive oxygen species (ROS) generation from several water-soluble fullerenes was examined. Macromolecular or small molecular water-soluble fullerene complexes/derivatives were prepared and their 1O2 and O2˙− generation abilities were evaluated by ESR spin-trapping methods. As a result, efficient 1O2 generation was detected from photoexcited C60, not only in organic solvents, but also in aqueous media and especially from small molecule C60–carboxylic acid derivatives. Whereas efficient O2˙− generation was observed in the aqueous solution of the C60/γ-CD complex under photoirradiation.
- This article is part of the themed collection: New Advances in Carbon Nanomaterials