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Issue 11, 2015
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Towards the elaboration of new gold-based optical theranostics

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Abstract

Four new red BODIPY–gold(I) theranostic compounds were synthesized. Some of them were vectorized by tethering a biovector (glucose or bombesin derivatives) to the metallic center. Their photophysical properties were studied. Additionally, their cytotoxicity was examined on different cancer cell lines and on a normal cell line, they were tracked in vitro by fluorescence detection, and their uptake was evaluated by ICP-MS measurements.

Graphical abstract: Towards the elaboration of new gold-based optical theranostics

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Publication details

The article was received on 30 Sep 2014, accepted on 28 Nov 2014 and first published on 28 Nov 2014


Article type: Paper
DOI: 10.1039/C4DT02977A
Dalton Trans., 2015,44, 4874-4883

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    Towards the elaboration of new gold-based optical theranostics

    P. Doulain, R. Decréau, C. Racoeur, V. Goncalves, L. Dubrez, A. Bettaieb, P. Le Gendre, F. Denat, C. Paul, C. Goze and E. Bodio, Dalton Trans., 2015, 44, 4874
    DOI: 10.1039/C4DT02977A

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