Issue 17, 2014

Point-of-care biochemical assays using gold nanoparticle-implemented microfluidics

Abstract

One of the goals of point-of-care (POC) is a chip-based, miniaturized, portable, self-containing system that allows the assay of proteins, nucleic acids, and cells in complex samples. The integration of nanomaterials and microfluidics can help achieve this goal. This tutorial review outlines the mechanism of assaying biomarkers by gold nanoparticles (AuNPs), and the implementation of AuNPs for microfluidic POC devices. In line with this, we discuss some recent advances in AuNP-coupled microfluidic sensors with enhanced performance. Portable and automated instruments for device operation and signal readout are also included for practical applications of these AuNP-combined microfluidic chips.

Graphical abstract: Point-of-care biochemical assays using gold nanoparticle-implemented microfluidics

Article information

Article type
Tutorial Review
Submitted
06 Apr 2014
First published
02 Jun 2014

Chem. Soc. Rev., 2014,43, 6239-6253

Author version available

Point-of-care biochemical assays using gold nanoparticle-implemented microfluidics

J. Sun, Y. Xianyu and X. Jiang, Chem. Soc. Rev., 2014, 43, 6239 DOI: 10.1039/C4CS00125G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements