Jump to main content
Jump to site search

Issue 13, 2014
Previous Article Next Article

Catalytic bismetallative multicomponent coupling reactions: scope, applications, and mechanisms

Author affiliations

Abstract

Catalytic reactions have played an indispensable role in organic chemistry for the last several decades. In particular, catalytic multicomponent reactions have attracted significant attention due to their efficiency and expediency towards complex molecule synthesis. The presence of bismetallic reagents (e.g. B–B, Si–Si, B–Si, Si–Sn, etc.) in this process renders the products enriched with various functional groups and multiple stereocenters. For this reason, catalytic bismetallative coupling is considered an effective method to generate the functional and stereochemical complexity of simple hydrocarbon substrates. This review highlights key developments of transition-metal catalyzed bismetallative reactions involving multiple π components. Specifically, it will highlight the scope, synthetic applications, and proposed mechanistic pathways of this process.

Graphical abstract: Catalytic bismetallative multicomponent coupling reactions: scope, applications, and mechanisms

Back to tab navigation

Article information


Submitted
30 Dec 2013
First published
16 Apr 2014

Chem. Soc. Rev., 2014,43, 4368-4380
Article type
Tutorial Review
Author version available

Catalytic bismetallative multicomponent coupling reactions: scope, applications, and mechanisms

H. Y. Cho and J. P. Morken, Chem. Soc. Rev., 2014, 43, 4368
DOI: 10.1039/C3CS60482A

Social activity

Search articles by author

Spotlight

Advertisements