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Issue 59, 2015
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A red-emitting ratiometric fluorescent probe based on a benzophosphole P-oxide scaffold for the detection of intracellular sodium ions

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Abstract

We disclose the development of a ratiometric fluorescent probe based on a benzophosphole P-oxide and its application for the detection of intracellular Na+ ions. Excitation by visible light induced red emission from this probe in water, which was subjected to a hypsochromic shift upon complexation with Na+. Based on this change, a ratiometric analysis enabled us to visualise changes in the Na+ concentration in living mammalian cells.

Graphical abstract: A red-emitting ratiometric fluorescent probe based on a benzophosphole P-oxide scaffold for the detection of intracellular sodium ions

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The article was received on 28 Apr 2015, accepted on 17 Jun 2015 and first published on 17 Jun 2015


Article type: Communication
DOI: 10.1039/C5CC03547C
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Citation: Chem. Commun., 2015,51, 11880-11883

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    A red-emitting ratiometric fluorescent probe based on a benzophosphole P-oxide scaffold for the detection of intracellular sodium ions

    M. Taki, H. Ogasawara, H. Osaki, A. Fukazawa, Y. Sato, K. Ogasawara, T. Higashiyama and S. Yamaguchi, Chem. Commun., 2015, 51, 11880
    DOI: 10.1039/C5CC03547C

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