Jump to main content
Jump to site search

Issue 10, 2015
Previous Article Next Article

Photo-induced sequence defined macromolecules via hetero bifunctional synthons

Author affiliations

Abstract

We report the first photochemical protocol for the generation of sequence defined macromolecules employing two hetero bifunctional photoreactive synthons, exploiting the orthogonal nature of photochemical – via the use of caged dienes – and thermally driven ligation protocols. We demonstrate that the iterative alternating synthon addition to an initial bifunctional core under irradiation at ambient temperature enables the generation of a macromolecule with up to 10 units (M = 3231.58 g mol−1, Đ = 1.00). The resulting macromolecules are monodisperse and feature absolute chain end fidelity. The unit-by-unit construction of the macromolecule is evidenced by Nuclear Magnetic Resonance Spectroscopy, Electrospray Ionization Mass Spectrometry and Size Exclusion Chromatography. The fundamental principle demonstrated herein paves the way for employing photochemical strategies for the design of sequence defined polymers.

Graphical abstract: Photo-induced sequence defined macromolecules via hetero bifunctional synthons

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Nov 2014, accepted on 03 Dec 2014 and first published on 03 Dec 2014


Article type: Communication
DOI: 10.1039/C4CC08756A
Author version
available:
Download author version (PDF)
Citation: Chem. Commun., 2015,51, 1799-1802
  •   Request permissions

    Photo-induced sequence defined macromolecules via hetero bifunctional synthons

    N. Zydziak, F. Feist, B. Huber, J. O. Mueller and C. Barner-Kowollik, Chem. Commun., 2015, 51, 1799
    DOI: 10.1039/C4CC08756A

Search articles by author

Spotlight

Advertisements