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Issue 98, 2014
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Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)

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Abstract

Individual micron-sized solid particles from a SalamolĀ® pharmaceutical inhaler are stably captured in air using an optical trap for the first time. Raman spectroscopy of the levitated particles allows online interrogation of composition and deliquescent phase change within a high humidity environment that mimics the particle's travel from inhaler to lung.

Graphical abstract: Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)

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Publication details

The article was received on 25 Jul 2014, accepted on 06 Oct 2014 and first published on 06 Oct 2014


Article type: Communication
DOI: 10.1039/C4CC05803H
Chem. Commun., 2014,50, 15499-15502

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    Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)

    H.-J. Tong, C. Fitzgerald, P. J. Gallimore, M. Kalberer, M. K. Kuimova, P. C. Seville, A. D. Ward and F. D. Pope, Chem. Commun., 2014, 50, 15499
    DOI: 10.1039/C4CC05803H

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