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Issue 78, 2014
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A highly selective sulfinate ester probe for thiol bioimaging

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Abstract

We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed.

Graphical abstract: A highly selective sulfinate ester probe for thiol bioimaging

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Article information


Submitted
15 Jul 2014
Accepted
06 Aug 2014
First published
06 Aug 2014

Chem. Commun., 2014,50, 11533-11535
Article type
Communication
Author version available

A highly selective sulfinate ester probe for thiol bioimaging

S. R. Malwal, A. Labade, A. S. Andhalkar, K. Sengupta and H. Chakrapani, Chem. Commun., 2014, 50, 11533
DOI: 10.1039/C4CC05462H

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