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Issue 78, 2014
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A highly selective sulfinate ester probe for thiol bioimaging

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Abstract

We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed.

Graphical abstract: A highly selective sulfinate ester probe for thiol bioimaging

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Publication details

The article was received on 15 Jul 2014, accepted on 06 Aug 2014 and first published on 06 Aug 2014


Article type: Communication
DOI: 10.1039/C4CC05462H
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Chem. Commun., 2014,50, 11533-11535

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    A highly selective sulfinate ester probe for thiol bioimaging

    S. R. Malwal, A. Labade, A. S. Andhalkar, K. Sengupta and H. Chakrapani, Chem. Commun., 2014, 50, 11533
    DOI: 10.1039/C4CC05462H

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