Jump to main content
Jump to site search

Issue 86, 2014
Previous Article Next Article

Design of anticoagulant surfaces based on cellulose nanocrystals

Author affiliations

Abstract

The anticoagulant activity of surfaces decorated with cellulose nanocrystals (CNCs) prepared via sulfuric acid hydrolysis, is explored. Such surfaces bear a high amount of negatively charged sulfate groups, which mimic the naturally occurring anticoagulant heparin in terms of charge density. It is demonstrated that CNC decorated surfaces significantly enhance the coagulation times of blood plasma and whole blood as proven by QCM-D and simple clotting tests.

Graphical abstract: Design of anticoagulant surfaces based on cellulose nanocrystals

Back to tab navigation

Supplementary files

Article information


Submitted
08 Jul 2014
Accepted
08 Sep 2014
First published
16 Sep 2014

Chem. Commun., 2014,50, 13070-13072
Article type
Communication
Author version available

Design of anticoagulant surfaces based on cellulose nanocrystals

H. M. A. Ehmann, T. Mohan, M. Koshanskaya, S. Scheicher, D. Breitwieser, V. Ribitsch, K. Stana-Kleinschek and S. Spirk, Chem. Commun., 2014, 50, 13070
DOI: 10.1039/C4CC05254D

Social activity

Search articles by author

Spotlight

Advertisements