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Issue 60, 2014
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Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels

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Abstract

A hybrid hydrogel based on collagen-mimetic peptides has been designed with tunable thermosensitive properties. By changing the number of POG repeats within the collagen peptide sequence, the thermal stability of the triple helical physical crosslinks of a peptide–polymer conjugate can be altered, thus tuning the stiffness of the hydrogel as a function of temperature. This report focuses on three different thermally responsive collagen peptide, PEG-based hydrogels and validates their use as stimuli-responsive materials.

Graphical abstract: Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels

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Supplementary files

Article information


Submitted
29 Apr 2014
Accepted
05 Jun 2014
First published
05 Jun 2014

Chem. Commun., 2014,50, 8174-8176
Article type
Communication
Author version available

Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels

C. M. Rubert Pérez, L. A. Rank and J. Chmielewski, Chem. Commun., 2014, 50, 8174
DOI: 10.1039/C4CC03171G

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