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Issue 56, 2014
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Separation and enrichment of enantiopure from racemic compounds using magnetic levitation

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Abstract

Crystallization of a solution with high enantiomeric excess can generate a mixture of crystals of the desired enantiomer and the racemic compound. Using a mixture of S-/RS-ibuprofen crystals as a model, we demonstrated that magnetic levitation (MagLev) is a useful technique for analysis, separation and enantioenrichment of chiral/racemic products.

Graphical abstract: Separation and enrichment of enantiopure from racemic compounds using magnetic levitation

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Article information


Submitted
08 Apr 2014
Accepted
21 May 2014
First published
21 May 2014

Chem. Commun., 2014,50, 7548-7551
Article type
Communication
Author version available

Separation and enrichment of enantiopure from racemic compounds using magnetic levitation

X. Yang, S. Y. Wong, D. K. Bwambok, M. B. J. Atkinson, X. Zhang, G. M. Whitesides and A. S. Myerson, Chem. Commun., 2014, 50, 7548
DOI: 10.1039/C4CC02604G

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