Jump to main content
Jump to site search
Publishing
Advanced

Issue 62, 2014
Previous Article Next Article

An expedient approach to pyrrolo[3,2-c]quinolines via regioselective formation of the pyrrole nucleus over indoles†

Manjusha V. Karkhelikar,a   Rajeev R. Jha,b   B. Sridhar,c   Pravin R. Likhar*a  and  Akhilesh K. Verma*b  
Author affiliations

* Corresponding authors

a Organometallic Group, Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Hyderabad-500007, India
E-mail: plikhar@iict.res.in

b Department of Chemistry, University of Delhi, Delhi-110007, India
E-mail: averma@acbr.du.ac.in

c X-Ray Crystallography Center, Indian Institute of Chemical Technology, Hyderabad-500007, India

Abstract

An efficient approach for the synthesis of pyrrolo[3,2-c]quinolines (the core nucleus of the natural product martinellic acid) from protected 2-alkynylanilines via the regioselective formation of pyrroles followed by Heck and intramolecular Michael addition has been described.

Graphical abstract: An expedient approach to pyrrolo[3,2-c]quinolines via regioselective formation of the pyrrole nucleus over indoles

Back to tab navigation
Download options Please wait...

Supplementary files

Article information

https://doi.org/10.1039/C4CC02466D
Submitted
03 Apr 2014
Accepted
07 May 2014
First published
20 Jun 2014
Chem. Commun., 2014,50, 8526-8528
Article type
Communication
Author version available
Download author version (PDF)
Permissions
Request permissions

An expedient approach to pyrrolo[3,2-c]quinolines via regioselective formation of the pyrrole nucleus over indoles

M. V. Karkhelikar, R. R. Jha, B. Sridhar, P. R. Likhar and A. K. Verma, Chem. Commun., 2014, 50, 8526
DOI: 10.1039/C4CC02466D

If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using Copyright Clearance Center. Go to our Instructions for using Copyright Clearance Center page for details.

Authors contributing to RSC publications (journal articles, books or book chapters) do not need to formally request permission to reproduce material contained in this article provided that the correct acknowledgement is given with the reproduced material.

Reproduced material should be attributed as follows:

  • For reproduction of material from NJC:
    Reproduced from Ref. XX with permission from the Centre National de la Recherche Scientifique (CNRS) and The Royal Society of Chemistry.
  • For reproduction of material from PCCP:
    Reproduced from Ref. XX with permission from the PCCP Owner Societies.
  • For reproduction of material from PPS:
    Reproduced from Ref. XX with permission from the European Society for Photobiology, the European Photochemistry Association, and The Royal Society of Chemistry.
  • For reproduction of material from all other RSC journals and books:
    Reproduced from Ref. XX with permission from The Royal Society of Chemistry.

If the material has been adapted instead of reproduced from the original RSC publication "Reproduced from" can be substituted with "Adapted from".

In all cases the Ref. XX is the XXth reference in the list of references.

If you are the author of this article you do not need to formally request permission to reproduce figures, diagrams etc. contained in this article in third party publications or in a thesis or dissertation provided that the correct acknowledgement is given with the reproduced material.

Reproduced material should be attributed as follows:

  • For reproduction of material from NJC:
    [Original citation] - Reproduced by permission of The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC
  • For reproduction of material from PCCP:
    [Original citation] - Reproduced by permission of the PCCP Owner Societies
  • For reproduction of material from PPS:
    [Original citation] - Reproduced by permission of The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC
  • For reproduction of material from all other RSC journals:
    [Original citation] - Reproduced by permission of The Royal Society of Chemistry

If you are the author of this article you still need to obtain permission to reproduce the whole article in a third party publication with the exception of reproduction of the whole article in a thesis or dissertation.

Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Social activity

Search articles by author

Spotlight

Advertisements