Trimethylaluminum and molecular oxygen are used in tandem to interrupt the Nazarov cyclization. α-Hydroxycyclopentanones are produced in moderate to good yield as a mixture of epimers. This sequence is the first example of combined nucleophilic/electrophilic trapping of the Nazarov oxyallyl intermediate.
Y. Kwon, O. Scadeng, R. McDonald and F. G. West, Chem. Commun., 2014, 50, 5558 DOI: 10.1039/C4CC02330G
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