Issue 33, 2014

Boronic acid chemistry in MALDI MS: a step forward in designing a reactive matrix with molecular recognition capabilities

Abstract

A boronic analogue of the archetype matrix α-cyano-4-hydroxycinnamic acid (CHCA) has been synthesised providing a new “reactive matrix” that possesses molecular recognition properties. This matrix selectively recognizes vic-diols, α-hydroxyacids, aminols and first allowed the detection of anions as fluoride (unaffordable by usual matrices).

Graphical abstract: Boronic acid chemistry in MALDI MS: a step forward in designing a reactive matrix with molecular recognition capabilities

Supplementary files

Article information

Article type
Communication
Submitted
14 Feb 2014
Accepted
07 Mar 2014
First published
07 Mar 2014

Chem. Commun., 2014,50, 4322-4324

Boronic acid chemistry in MALDI MS: a step forward in designing a reactive matrix with molecular recognition capabilities

A. Monopoli, C. D. Calvano, A. Nacci and F. Palmisano, Chem. Commun., 2014, 50, 4322 DOI: 10.1039/C4CC01185F

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