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Issue 23, 2014
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Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ

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Abstract

Lactosyl ceramide analogues carrying novel bifunctional BODIPY-based fluorescent tags were designed and synthesised for live cell imaging. Addition of azide functionality on the fluorophore facilitated isobaric tagging for quantitative multiplexed analysis of biomolecules based on tandem mass spectrometry.

Graphical abstract: Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ

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Publication details

The article was received on 07 Jan 2014, accepted on 29 Jan 2014 and first published on 31 Jan 2014


Article type: Communication
DOI: 10.1039/C4CC00112E
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Citation: Chem. Commun., 2014,50, 3010-3013
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    Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ

    S. Son, S. Daikoku, A. Ohtake, K. Suzuki, K. Kabayama, Y. Ito and O. Kanie, Chem. Commun., 2014, 50, 3010
    DOI: 10.1039/C4CC00112E

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