Issue 33, 2014
From the journal:

Chemical Communications

Phosphorescent proteins for bio-imaging and site selective bio-conjugation of peptides and proteins with luminescent cyclometalated iridium(iii) complexes†

Hoi-Yan Shiu,ab   Hiu-Chi Chong,c   Yun-Chung Leung,c   Taotao Zouab  and  Chi-Ming Che*ab  

* Corresponding authors

a State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China
E-mail: cmche@hku.hk
Fax: +852 2857-1586

b HKU Shenzhen Institute of Research and Innovation, Shenzhen 518053, China

c Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China

Abstract

A new bio-conjugation reaction for site selective modification of proteins and peptides with phosphorescent iridium(III) complexes has been developed; the Ir(III)-modified proteins and peptides display long emission lifetimes and large Stoke shifts that can be used for bio-imaging studies.

Graphical abstract: Phosphorescent proteins for bio-imaging and site selective bio-conjugation of peptides and proteins with luminescent cyclometalated iridium(iii) complexes

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Article information

DOI
https://doi.org/10.1039/C3CC48376B
Article type
Communication
Submitted
01 Nov 2013
Accepted
07 Mar 2014
First published
19 Mar 2014

Chem. Commun., 2014,50, 4375-4378

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Phosphorescent proteins for bio-imaging and site selective bio-conjugation of peptides and proteins with luminescent cyclometalated iridium(III) complexes

H. Shiu, H. Chong, Y. Leung, T. Zou and C. Che, Chem. Commun., 2014, 50, 4375 DOI: 10.1039/C3CC48376B

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