We demonstrate the functional control of a dansylated polytheonamide mimic (2), an artificial ion channel-forming cytotoxic peptide, by the external addition of a polyclonal anti-dansyl antibody (anti-dansyl IgG). The IgG effectively suppressed the ion transport activity and cytotoxicity of 2 in a dose-dependent manner.
H. Itoh and M. Inoue, Chem. Commun., 2014, 50, 939 DOI: 10.1039/C3CC48348G
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