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A novel supramolecular three-input AND logic gate is demonstrated as a ‘lab-on-a-molecule’ for monitoring the Na+, pH and pE levels in solution by communicating a fluorescence signal. The fluorescence signal is modulated by three photoinduced electron transfer reactions that are controlled by an unprecedented combination of two cation binding events and one redox reaction.

Graphical abstract: A sodium-enabled ‘Pourbaix sensor’: a three-input AND logic gate as a ‘lab-on-a-molecule’ for monitoring Na+, pH and pE

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