Duc Trung Bui, Julien Nicolas, Andrei Maksimenko, Didier Desmaële and Patrick Couvreur
Chem. Commun., 2014,50, 5336-5338
DOI:
10.1039/C3CC47427E,
Communication
Fluorescent and biotinylated squalene–gemcitabine prodrug nanoparticles exhibiting high drug payloads have been prepared and successfully used to target different cancer cell lines, resulting in increased cell uptake and improved anticancer efficiency, which represents the first targeted system derived from the squalenoylation approach.
