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Synthetic [2-13C]mevalonolactone was fed to the gibberellin producer Fusarium fujikuroi and its incorporation into four known terpenoids was investigated by 13C NMR analysis of crude culture extracts. The experiments gave detailed insights into the mechanisms of terpene biosynthesis by this fungus.

Graphical abstract: Labelling studies on the biosynthesis of terpenes in Fusarium fujikuroi

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