Minsu Shon, Ramachandran Shanmugavel, Giyoung Shin, Sam Mathew, Sang-Hyeup Lee and Hyungdon Yun
Chem. Commun., 2014,50, 12680-12683
DOI:
10.1039/C3CC44864A,
Communication
In this study, we successfully synthesized enantiomerically pure (R)- and (S)-γ-amino acids (>99% ee) using ω-transaminase (ω-TA) through kinetic resolution and asymmetric synthesis respectively. The present study demonstrates the high potentiality of ω-TA reaction for the production of chiral γ-amino acids.
