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Issue 7, 2014

Non-invasive mouthguard biosensor for continuous salivary monitoring of metabolites

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Abstract

The present work describes the first example of a wearable salivary metabolite biosensor based on the integration of a printable enzymatic electrode on a mouthguard. The new mouthguard enzymatic biosensor, based on an immobilized lactate oxidase and a low potential detection of the peroxide product, exhibits high sensitivity, selectivity and stability using whole human saliva samples. Such non-invasive mouthguard metabolite biosensors could tender useful real-time information regarding a wearer's health, performance and stress level, and thus hold considerable promise for diverse biomedical and fitness applications.

Graphical abstract: Non-invasive mouthguard biosensor for continuous salivary monitoring of metabolites

Article information


Submitted
25 Dec 2013
Accepted
24 Jan 2014
First published
24 Jan 2014

Analyst, 2014,139, 1632-1636
Article type
Paper
Author version available

Non-invasive mouthguard biosensor for continuous salivary monitoring of metabolites

J. Kim, G. Valdés-Ramírez, A. J. Bandodkar, W. Jia, A. G. Martinez, J. Ramírez, P. Mercier and J. Wang, Analyst, 2014, 139, 1632 DOI: 10.1039/C3AN02359A

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