A click reaction (copper-catalyzed azide–alkyne cycloaddition) catalyzed by “naked” copper ions (without ligands) generated in situ from a copper substrate by laser ablation in a high-voltage assisted laser desorption/ionization (HALDI) ion source is demonstrated.
R. Qiu and H. Luo, Analyst, 2014, 139, 3706 DOI: 10.1039/C3AN02190D
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