Jump to main content
Jump to site search

Issue 43, 2014
Previous Article Next Article

Controlling self-assembly of microtubule spools via kinesin motor density

Author affiliations

Abstract

Active self-assembly, in which non-thermal energy is consumed by the system to put together building blocks, allows the creation of non-equilibrium structures and active materials. Microtubule spools assembled in gliding assays are one example of such non-equilibrium structures, capable of storing bending energies on the order of 105 kT. Although these structures arise spontaneously in experiments, the origin of microtubule spooling has long been debated. Here, using a stepwise kinesin gradient, we demonstrate that spool assembly can be controlled by the surface density of kinesin motors, showing that pinning of microtubules due to dead motors plays a dominant role in spool initiation.

Graphical abstract: Controlling self-assembly of microtubule spools via kinesin motor density

Back to tab navigation

Supplementary files

Article information


Submitted
10 Jul 2014
Accepted
16 Sep 2014
First published
16 Sep 2014

Soft Matter, 2014,10, 8731-8736
Article type
Paper
Author version available

Controlling self-assembly of microtubule spools via kinesin motor density

A. T. Lam, C. Curschellas, D. Krovvidi and H. Hess, Soft Matter, 2014, 10, 8731
DOI: 10.1039/C4SM01518E

Social activity

Search articles by author

Spotlight

Advertisements