Jump to main content
Jump to site search

Issue 12, 2014
Previous Article Next Article

Late-stage [18F]fluorination: new solutions to old problems

Author affiliations


The last 2–3 years have seen numerous relationships develop between organometallic chemists, fluorine chemists and PET Centers around the world. These collaborations have led to the development of many new strategies for the late-stage introduction of fluorine-18 into complex bioactive molecules. In this perspective we highlight recent developments and key milestones since 2011.

Graphical abstract: Late-stage [18F]fluorination: new solutions to old problems

Back to tab navigation

Publication details

The article was received on 15 Jul 2014, accepted on 21 Aug 2014 and first published on 25 Aug 2014

Article type: Perspective
DOI: 10.1039/C4SC02099E
Author version
Download author version (PDF)
Chem. Sci., 2014,5, 4545-4553

  •   Request permissions

    Late-stage [18F]fluorination: new solutions to old problems

    A. F. Brooks, J. J. Topczewski, N. Ichiishi, M. S. Sanford and P. J. H. Scott, Chem. Sci., 2014, 5, 4545
    DOI: 10.1039/C4SC02099E

Search articles by author