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Issue 52, 2014
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Gold nanoparticle-decorated MoS2 nanosheets for simultaneous detection of ascorbic acid, dopamine and uric acid

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Abstract

An electrochemical sensor has been developed for simultaneous detection of dopamine (DA), uric acid (UA) and ascorbic acid (AA) based on a gold nanoparticle-decorated MoS2 nanocomposite (AuNPs@MoS2) modified electrode. The AuNPs@MoS2 nanocomposite has been synthesized by electrodeposition of AuNPs on the MoS2 nanosheets, which possesses better properties than pure AuNPs and MoS2. The AuNPs@MoS2 film modified electrode showed excellent electrocatalytic activity toward the oxidation of AA, DA and UA with three well-resolved oxidation peaks. The peak separation of AA–DA, DA–UA and AA–UA is 151 mV, 137 mV and 288 mV, respectively, which permits the modified electrode to individually or simultaneously analyze AA, DA and UA by differential pulse voltammetry (DPV). Under optimum conditions, the AuNPs@MoS2 modified electrode exhibits linear response toward AA, DA and UA in the range of 50–100 000 μM, 0.05–30 μM and 50–40 000 μM, respectively. Moreover, the MoS2-based modified electrode was successfully employed to determine DA in human serum samples with satisfactory results.

Graphical abstract: Gold nanoparticle-decorated MoS2 nanosheets for simultaneous detection of ascorbic acid, dopamine and uric acid

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Publication details

The article was received on 03 May 2014, accepted on 13 Jun 2014 and first published on 13 Jun 2014


Article type: Paper
DOI: 10.1039/C4RA04046E
RSC Adv., 2014,4, 27625-27629

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    Gold nanoparticle-decorated MoS2 nanosheets for simultaneous detection of ascorbic acid, dopamine and uric acid

    H. Sun, J. Chao, X. Zuo, S. Su, X. Liu, L. Yuwen, C. Fan and L. Wang, RSC Adv., 2014, 4, 27625
    DOI: 10.1039/C4RA04046E

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