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Issue 38, 2014
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ZrCl4-promoted facile synthesis of indole derivatives

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Abstract

Zirconium(IV) chloride effectively activates nitrogen (N2) extrusion from aryl azidoacrylates followed by annulation to provide the desired indole products in moderate to good yields. The reaction proceeds at low temperature and in short reaction time and is applicable to a variety of substrates.

Graphical abstract: ZrCl4-promoted facile synthesis of indole derivatives

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Publication details

The article was received on 12 Mar 2014, accepted on 17 Apr 2014 and first published on 18 Apr 2014


Article type: Communication
DOI: 10.1039/C4RA02158D
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RSC Adv., 2014,4, 20048-20052

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    ZrCl4-promoted facile synthesis of indole derivatives

    J. Tummatorn, M. P. Gleeson, S. Krajangsri, C. Thongsornkleeb and S. Ruchirawat, RSC Adv., 2014, 4, 20048
    DOI: 10.1039/C4RA02158D

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