Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 100, 2014
Previous Article Next Article

Mesopattern of immobilised bone morphogenetic protein-2 created by microcontact printing and dip-pen nanolithography influence C2C12 cell fate

Author affiliations

Abstract

Dip-pen nanolithography and microcontact printing were used to fabricate mesopatterned substrates for cell differentiation experiments. A biotin–thiol was patterned on gold substrates and subsequently functionalised with streptavidin and biotinylated bone morphogenetic protein-2 (BMP-2). The feasibility of mesopatterned substrates containing immobilised BMP-2 was proven by obtaining similar differentiation outcomes compared to the growth factor in solution. Therefore, these substrates might be suitable for replacing conventional experiments with BMP-2 in solution.

Graphical abstract: Mesopattern of immobilised bone morphogenetic protein-2 created by microcontact printing and dip-pen nanolithography influence C2C12 cell fate

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Sep 2014, accepted on 27 Oct 2014 and first published on 27 Oct 2014


Article type: Communication
DOI: 10.1039/C4RA10311D
Author version
available:
Download author version (PDF)
RSC Adv., 2014,4, 56809-56815

  •   Request permissions

    Mesopattern of immobilised bone morphogenetic protein-2 created by microcontact printing and dip-pen nanolithography influence C2C12 cell fate

    S. Oberhansl, A. G. Castaño, A. Lagunas, E. Prats-Alfonso, M. Hirtz, F. Albericio, H. Fuchs, J. Samitier and E. Martinez, RSC Adv., 2014, 4, 56809
    DOI: 10.1039/C4RA10311D

Search articles by author

Spotlight

Advertisements