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Issue 95, 2014

Acceptorless dehydrogenative synthesis of 2-substituted quinazolines from 2-aminobenzylamine with primary alcohols or aldehydes by heterogeneous Pt catalysts

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Abstract

CeO2-supported Pt nanoparticle catalysts enabled the acceptorless dehydrogenative synthesis of 2-substituted quinazolines from 2-aminobenzylamine with aliphatic and benzyl primary alcohols or aldehydes with low catalyst loading, wide substrate scope and good catalyst reusability, demonstrating the first acceptor-free and additive-free catalytic system for this reaction.

Graphical abstract: Acceptorless dehydrogenative synthesis of 2-substituted quinazolines from 2-aminobenzylamine with primary alcohols or aldehydes by heterogeneous Pt catalysts

Supplementary files

Article information


Submitted
25 Aug 2014
Accepted
09 Oct 2014
First published
09 Oct 2014

RSC Adv., 2014,4, 53374-53379
Article type
Communication

Acceptorless dehydrogenative synthesis of 2-substituted quinazolines from 2-aminobenzylamine with primary alcohols or aldehydes by heterogeneous Pt catalysts

C. Chaudhari, S. M. A. Hakim Siddiki, M. Tamura and K. Shimizu, RSC Adv., 2014, 4, 53374 DOI: 10.1039/C4RA09205H

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