Jump to main content
Jump to site search

Issue 105, 2014
Previous Article Next Article

Advantageous asymmetric ketone reduction with a competitive hydrogenation/transfer hydrogenation system using chiral bifunctional iridium catalysts

Author affiliations

Abstract

Hydrogenation of aromatic ketones with chiral bifunctional amidoiridium complexes proceeds in preference to transfer hydrogenation in methanol, in which the pressurised hydrogen can suppress unintended racemisation of the alcoholic product, leading to enhanced enantioselectivity.

Graphical abstract: Advantageous asymmetric ketone reduction with a competitive hydrogenation/transfer hydrogenation system using chiral bifunctional iridium catalysts

Back to tab navigation

Supplementary files

Article information


Submitted
31 Jul 2014
Accepted
23 Oct 2014
First published
23 Oct 2014

RSC Adv., 2014,4, 61001-61004
Article type
Communication
Author version available

Advantageous asymmetric ketone reduction with a competitive hydrogenation/transfer hydrogenation system using chiral bifunctional iridium catalysts

J. Moritani, Y. Kayaki and T. Ikariya, RSC Adv., 2014, 4, 61001
DOI: 10.1039/C4RA07854C

Social activity

Search articles by author

Spotlight

Advertisements