Jump to main content
Jump to site search

Issue 65, 2014
Previous Article Next Article

Integrated bioprinting and imaging for scalable, networkable desktop experimentation

Author affiliations

Abstract

Adaptations of mass-market consumer electronics are increasingly used to aid experimentation in engineering, life sciences, and education. Inspired by recent bioprinting and imaging research, we have developed a low-cost, networkable, scalable bioprinter with integrated imaging that enables automated fluid deposition with monitoring biological materials over a large area that can interface with standard plasticware. We re-engineered a desktop printer and scanner with mechanical workarounds (rather than software) to leverage the unmodified software, creating a complete system for ∼$700. We found that the resulting print accuracy and precision of this system were close to those of the unmodified printer and scanner. We demonstrate the reach of this system by printing multiple strains of Escherichia coli, performing quantitative time-lapse recordings of bacterial growth, and then separating different fluorescent strains according to color. A fluid-deposition and imaging platform, like the one developed here, could be integrated for do-it-yourself research, remote experimentation, and (on-line) education.

Graphical abstract: Integrated bioprinting and imaging for scalable, networkable desktop experimentation

Back to tab navigation

Supplementary files

Article information


Submitted
18 Jun 2014
Accepted
07 Jul 2014
First published
08 Jul 2014

RSC Adv., 2014,4, 34721-34728
Article type
Paper
Author version available

Integrated bioprinting and imaging for scalable, networkable desktop experimentation

N. D. Orloff, C. Truong, N. Cira, S. Koo, A. Hamilton, S. Choi, V. Wu and I. H. Riedel-Kruse, RSC Adv., 2014, 4, 34721 DOI: 10.1039/C4RA05932H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements