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Issue 21, 2014
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Carbon-based quantum dots for fluorescence imaging of cells and tissues

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Abstract

Carbon dots (or carbon quantum dots in some literature reports), generally small carbon nanoparticles with various surface passivation effects, have attracted widespread attention in recent years, with a rapidly increasing number of research publications. The reported studies covered many aspects of carbon dots, from the development of many new synthetic methodologies to an improved mechanistic elucidation and to the exploration of application opportunities, especially for those in the fluorescence imaging of cells and tissues. There have also been significant advances in the establishment of a shared mechanistic framework for carbon dots and other carbon-based quantum dots, graphene quantum dots in particular. In this article, representative recent studies for more efficient syntheses of better-performing carbon dots are highlighted along with results from explorations of their various bioimaging applications in vitro and in vivo. Similar fluorescence properties and potential imaging uses of some graphene quantum dots are also discussed, toward a more consistent and uniform understanding of phenomenologically different carbon-based quantum dots.

Graphical abstract: Carbon-based quantum dots for fluorescence imaging of cells and tissues

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Article information


Submitted
16 Dec 2013
Accepted
05 Feb 2014
First published
05 Feb 2014

RSC Adv., 2014,4, 10791-10807
Article type
Review Article

Carbon-based quantum dots for fluorescence imaging of cells and tissues

P. G. Luo, F. Yang, S. Yang, S. K. Sonkar, L. Yang, J. J. Broglie, Y. Liu and Y. Sun, RSC Adv., 2014, 4, 10791 DOI: 10.1039/C3RA47683A

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