Jump to main content
Jump to site search

Issue 31, 2015
Previous Article Next Article

Functional, sub-100 nm polymer nanoparticles via thiol–ene miniemulsion photopolymerization

Author affiliations

Abstract

In this work, sub-100 nm crosslinked polythioether nanoparticles were synthesized via thiol–ene photopolymerization in miniemulsion using high-energy homogenization. The effects of the miniemulsion formulation and homogenization parameters – including inhibitor concentration, surfactant concentration, organic weight fraction, ultrasonication time and amplitude – on nanoparticle size and size distribution were investigated. Thiol–ene nanoparticles with a mean particle diameter of 46 nm were obtained under optimized conditions for the current system at 2.5 wt% organic fraction and 20 mM surfactant concentration. In an effort to demonstrate potential utility of thiol–ene nanoparticles, we exploit the step-growth radical mechanism of thiol–ene photopolymerization under non-stoichiometric conditions to fabricate functional nanoparticles that express excess thiol or alkene at the particle surface. We show that these excess functional groups can be utilized as reactive handles in thiol-Michael and radical-mediated thiol–ene reactions for immobilization of fluorescent moieties via postpolymerization modification.

Graphical abstract: Functional, sub-100 nm polymer nanoparticles via thiol–ene miniemulsion photopolymerization

Back to tab navigation

Supplementary files

Publication details

The article was received on 24 Oct 2014, accepted on 20 Nov 2014 and first published on 21 Nov 2014


Article type: Paper
DOI: 10.1039/C4PY01449A
Author version
available:
Download author version (PDF)
Citation: Polym. Chem., 2015,6, 5625-5632
  •   Request permissions

    Functional, sub-100 nm polymer nanoparticles via thiol–ene miniemulsion photopolymerization

    D. V. Amato, D. N. Amato, A. S. Flynt and D. L. Patton, Polym. Chem., 2015, 6, 5625
    DOI: 10.1039/C4PY01449A

Search articles by author

Spotlight

Advertisements