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Issue 10, 2014
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Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

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Abstract

This mini-review highlights the latest advances in the chemistry and biology of Pluronic® triblock copolymers. We focus on their applications in medicine, as drug delivery carriers, biological response modifiers, and pharmaceutical ingredients. Examples of drug delivery systems and formulations currently in clinical use, clinical trials or preclinical development are highlighted. We also discuss the role that Pluronic® copolymers may play in the innovative design of new nanomedicines in the near future.

Graphical abstract: Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

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Article information


Submitted
11 Jan 2014
Accepted
11 Feb 2014
First published
24 Mar 2014

This article is Open Access

Polym. Chem., 2014,5, 3291-3297
Article type
Minireview

Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

A. Pitto-Barry and N. P. E. Barry, Polym. Chem., 2014, 5, 3291
DOI: 10.1039/C4PY00039K

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