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Issue 5, 2014
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Phenylboronic acid-based glucose-responsive polymeric nanoparticles: synthesis and applications in drug delivery

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Abstract

Glucose-responsive materials have attracted great intention in recent years due to their potential application in drug delivery. Phenylboronic acid-containing materials have been most widely studied and used in construction of glucose-responsive system for insulin delivery. This review covers the recent advances in synthesis of phenylboronic acid-based glucose-responsive materials, especially in forms of nanogels (microgels), micelles, vesicles, and mesoporous silica nanoparticles. Applications of these nanomaterials in drug delivery are discussed.

Graphical abstract: Phenylboronic acid-based glucose-responsive polymeric nanoparticles: synthesis and applications in drug delivery

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Article information


Submitted
01 Sep 2013
Accepted
10 Oct 2013
First published
11 Oct 2013

Polym. Chem., 2014,5, 1503-1518
Article type
Review Article

Phenylboronic acid-based glucose-responsive polymeric nanoparticles: synthesis and applications in drug delivery

R. Ma and L. Shi, Polym. Chem., 2014, 5, 1503
DOI: 10.1039/C3PY01202F

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