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Issue 24, 2016
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Probing the self-assembly and stability of oligohistidine based rod-like micelles by aggregation induced luminescence

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Abstract

The synthesis and self-assembly of a new C2-symmetric oligohistidine amphiphile equipped with an aggregation induced emission luminophore is reported. We observe the formation of highly stable and ordered rod-like micelles in phosphate buffered saline, with a critical aggregation concentration below 200 nM. Aggregation induced emission of the luminophore confirms the high stability of the anisotropic assemblies in serum.

Graphical abstract: Probing the self-assembly and stability of oligohistidine based rod-like micelles by aggregation induced luminescence

  • This article is part of the themed collection: New Talent
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Supplementary files

Article information


Submitted
04 Feb 2016
Accepted
07 Mar 2016
First published
08 Mar 2016

This article is Open Access

Org. Biomol. Chem., 2016,14, 5574-5579
Article type
Communication

Probing the self-assembly and stability of oligohistidine based rod-like micelles by aggregation induced luminescence

H. Frisch, D. Spitzer, M. Haase, T. Basché, J. Voskuhl and P. Besenius, Org. Biomol. Chem., 2016, 14, 5574
DOI: 10.1039/C6OB00292G

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