Jump to main content
Jump to site search

Issue 36, 2014
Previous Article Next Article

Ratiometric fluorescence chemosensor based on tyrosine derivatives for monitoring mercury ions in aqueous solutions

Author affiliations

Abstract

Ratiometric fluorescent chemosensors 1 and 2 were synthesized based on tyrosine amino acid derivatives with a pyrene fluorophore. 1 and 2 showed high selectivity for Hg(II) ions among 13 metal ions in aqueous solutions. Both 1 and 2 sensitively detected Hg(II) ions in aqueous solutions by ratiometric response without interference of any of the other tested metal ions including Cu(II), Cd(II), Pb(II), and Ag(I) ions. 1 and 2 had tight binding affinities (5.72 × 1013 M−2, 1.15 × 1013 M−2) for Hg(II) with nano-molar detection limits. The binding mode was characterized with the help of organic spectroscopic data, which revealed that the methoxyphenyl moieties of 1 and 2 played a vital role in the coordination of Hg(II). The deprotonation of the sulfonamide group is not a critical process for the binding of mercury ions. The methoxyphenyl moiety, sulfonamide group, and the C-terminal amide moiety of 1 and 2 as ligands for Hg(II) played crucial roles in the stabilization of the 2 : 1 complexes.

Graphical abstract: Ratiometric fluorescence chemosensor based on tyrosine derivatives for monitoring mercury ions in aqueous solutions

Back to tab navigation

Supplementary files

Article information


Submitted
21 May 2014
Accepted
17 Jul 2014
First published
17 Jul 2014

Org. Biomol. Chem., 2014,12, 7100-7109
Article type
Paper
Author version available

Ratiometric fluorescence chemosensor based on tyrosine derivatives for monitoring mercury ions in aqueous solutions

P. Thirupathi, P. Saritha (née Gudelli) and K. Lee, Org. Biomol. Chem., 2014, 12, 7100
DOI: 10.1039/C4OB01044B

Social activity

Search articles by author

Spotlight

Advertisements