Jump to main content
Jump to site search

Issue 18, 2014
Previous Article Next Article

Gold-catalysed cyclisation of N-propargylic β-enaminones to form 3-methylene-1-pyrroline derivatives

Author affiliations

Abstract

A gold(I) catalysed reaction between N-propargylic β-enaminones and arynes was developed to access 3-methylene-1-pyrrolines. The title compounds were obtained in 57–78% yields. This reaction is useful for the generation of substituted 1-pyrrolines exhibiting significant molecular complexity.

Graphical abstract: Gold-catalysed cyclisation of N-propargylic β-enaminones to form 3-methylene-1-pyrroline derivatives

Back to tab navigation

Supplementary files

Article information


Submitted
16 Dec 2013
Accepted
13 Feb 2014
First published
13 Feb 2014

Org. Biomol. Chem., 2014,12, 2869-2873
Article type
Communication
Author version available

Gold-catalysed cyclisation of N-propargylic β-enaminones to form 3-methylene-1-pyrroline derivatives

K. Goutham, N. S. V. M. R. Mangina, S. Suresh, P. Raghavaiah and G. V. Karunakar, Org. Biomol. Chem., 2014, 12, 2869
DOI: 10.1039/C3OB42513D

Social activity

Search articles by author

Spotlight

Advertisements