Cross-coupling/annulations of quinazolones with alkynes for access to fused polycyclic heteroarenes under mild conditions†
Abstract
Ruthenium-catalyzed regioselective oxidative cross-coupling/annulations of quinazolones with alkynes were successfully developed for direct access to fused polycyclic heteroarenes. The transformation proceeded well with a broad substrate scope under mild conditions to achieve moderate to high yields.