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Issue 4, 2014
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Trying to rationalize total synthesis

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Abstract

Covering: 1998 to 2013

Total synthesis has been held in high esteem for many decades. In recent years, however, public opinion has turned more and more skeptical. In particular, long and uneventful sequences towards complex yet useless targets are considered a waste of resources and are refused funding. There is only one way to remedy this unpleasant situation: total synthesis must be efficient and present attractive chemistry. This article tries to show some aspects on how this increase in efficiency might be achieved.

Graphical abstract: Trying to rationalize total synthesis

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Publication details

The article was received on 03 Oct 2013 and first published on 04 Mar 2014


Article type: Review Article
DOI: 10.1039/C3NP70105K
Nat. Prod. Rep., 2014,31, 595-603

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    Trying to rationalize total synthesis

    J. Mulzer, Nat. Prod. Rep., 2014, 31, 595
    DOI: 10.1039/C3NP70105K

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