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Issue 13, 2014
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Frontier microfluidic techniques for short and long-term single cell analysis

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Abstract

Here, we review the frontier microfluidic techniques for single cell analysis (SCA), which is important for research of many biological systems. Microfluidics provides high-throughput, high-resolution experiments at low cost and reagent use, making it especially useful for single cell analysis. Recent advancements in the field have made SCA more feasible, improving device throughput and resolution, adding capabilities, and combining different functions to bring forth new assays. Developments in incubation have allowed for long-term cell tracking assays to be performed with single cell resolution. The ability of systems to provide chemical isolation or prolonged growth of adherent cells is also discussed.

Graphical abstract: Frontier microfluidic techniques for short and long-term single cell analysis

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Publication details

The article was received on 05 Jan 2014, accepted on 17 Feb 2014 and first published on 17 Feb 2014


Article type: Frontier
DOI: 10.1039/C4LC00013G
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Lab Chip, 2014,14, 2161-2167

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    Frontier microfluidic techniques for short and long-term single cell analysis

    J. Avesar, T. B. Arye and S. Levenberg, Lab Chip, 2014, 14, 2161
    DOI: 10.1039/C4LC00013G

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