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Issue 3, 2014
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Oxygen levels in thermoplastic microfluidic devices during cell culture

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Abstract

We developed a computational model to predict oxygen levels in microfluidic plastic devices during cell culture. This model is based on experimental evaluation of oxygen levels. Conditions are determined that provide adequate oxygen supply to two cell types, hepatocytes and endothelial cells, either by diffusion through the plastic device, or by supplying a low flow rate of medium.

Graphical abstract: Oxygen levels in thermoplastic microfluidic devices during cell culture

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Publication details

The article was received on 10 Oct 2013, accepted on 25 Nov 2013 and first published on 25 Nov 2013


Article type: Communication
DOI: 10.1039/C3LC51160J
Lab Chip, 2014,14, 459-462

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    Oxygen levels in thermoplastic microfluidic devices during cell culture

    C. J. Ochs, J. Kasuya, A. Pavesi and R. D. Kamm, Lab Chip, 2014, 14, 459
    DOI: 10.1039/C3LC51160J

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