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Issue 93, 2014
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Antibacterial polymeric nanostructures for biomedical applications

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Abstract

The high incidence of bacterial infection and the growing resistance of bacteria to conventional antibiotics have resulted in the strong need for the development of new generation of antibiotics. Nano-sized particles have been considered as novel antibacterial agents with high surface area and high reactivity. The overall antibacterial properties of antimicrobial nanostructures can be significantly enhanced compared with conventional antibacterial agents not in a regular nanostructure, showing a better effect in inhibiting the growth and reproduction of microbials such as bacteria and fungi, etc. In this review, recent advances in the research and applications of antimicrobial polymeric nanostructures have been highlighted, including silver-decorated polymer micelles and vesicles, antimicrobial polymer micelles and vesicles, and antimicrobial peptide-based vesicles, etc. Furthermore, we proposed the current challenges and future research directions in the field of antibacterial polymeric nanostructures for the real-world biomedical applications.

Graphical abstract: Antibacterial polymeric nanostructures for biomedical applications

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Publication details

The article was received on 23 Apr 2014, accepted on 31 Jul 2014 and first published on 31 Jul 2014


Article type: Feature Article
DOI: 10.1039/C4CC03001J
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Chem. Commun., 2014,50, 14482-14493

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    Antibacterial polymeric nanostructures for biomedical applications

    J. Chen, F. Wang, Q. Liu and J. Du, Chem. Commun., 2014, 50, 14482
    DOI: 10.1039/C4CC03001J

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