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Issue 56, 2014
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A fluorescent probe for imaging symmetric and asymmetric cell division in neurosphere formation

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Abstract

We report here a novel fluorescent chemical probe CDy5 which stains distinct neural stem/progenitor cells (NSPCs) by binding to acid ceramidase in mouse neurospheres. CDy5 is distributed evenly or unevenly to the daughter cells during multiple mitoses enabling the live imaging of symmetric and asymmetric divisions of isolated NSPCs.

Graphical abstract: A fluorescent probe for imaging symmetric and asymmetric cell division in neurosphere formation

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Article information


Submitted
22 Apr 2014
Accepted
22 May 2014
First published
22 May 2014

Chem. Commun., 2014,50, 7492-7494
Article type
Communication
Author version available

A fluorescent probe for imaging symmetric and asymmetric cell division in neurosphere formation

S. Yun, C. Leong, X. Bi, H. Ha, Y. H. Yu, Y. L. Tan, G. Narayanan, S. Sankaran, J. Kim, S. Hariharan, S. Ahmed and Y. Chang, Chem. Commun., 2014, 50, 7492
DOI: 10.1039/C4CC02974G

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