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Issue 23, 2014
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Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ

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Abstract

Lactosyl ceramide analogues carrying novel bifunctional BODIPY-based fluorescent tags were designed and synthesised for live cell imaging. Addition of azide functionality on the fluorophore facilitated isobaric tagging for quantitative multiplexed analysis of biomolecules based on tandem mass spectrometry.

Graphical abstract: Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ

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Supplementary files

Article information


Submitted
07 Jan 2014
Accepted
29 Jan 2014
First published
31 Jan 2014

Chem. Commun., 2014,50, 3010-3013
Article type
Communication
Author version available

Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ

S. Son, S. Daikoku, A. Ohtake, K. Suzuki, K. Kabayama, Y. Ito and O. Kanie, Chem. Commun., 2014, 50, 3010
DOI: 10.1039/C4CC00112E

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