Issue 7, 2014

Dendrimer-like polymeric DNAs as chemiluminescence probes for amplified detection of telomere DNA on a solid-phase membrane

Abstract

For the first time, an amplified chemiluminescence (CL) detection of the telomere DNA spotted on a nylon membrane is described here, based on the direct hybridization with the CL probe of dendrimer-like polymeric DNAs possessing a large number of guanine moieties. This probe was synthesized by sense and antisense hybridization between Y-shaped DNAs and then could hybridize with the target DNA.

Graphical abstract: Dendrimer-like polymeric DNAs as chemiluminescence probes for amplified detection of telomere DNA on a solid-phase membrane

Supplementary files

Article information

Article type
Communication
Submitted
29 Sep 2013
Accepted
12 Nov 2013
First published
02 Dec 2013

Chem. Commun., 2014,50, 859-861

Dendrimer-like polymeric DNAs as chemiluminescence probes for amplified detection of telomere DNA on a solid-phase membrane

A. F. M. El-Mahdy, T. Shibata, T. Kabashima and M. Kai, Chem. Commun., 2014, 50, 859 DOI: 10.1039/C3CC47454B

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