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Issue 7, 2014
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Application of biomaterials for the detection of amyloid aggregates

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Abstract

Amyloid aggregates, which include oligomers and fibrils, are considered to cause various diseases, and their detection is important. In this minireview, recent developments on biomaterials, such as proteins, nanoparticles, and chemical reagents, for detecting amyloid aggregates are discussed. In particular, the molecular chaperone prefoldin (PFD) exhibits interesting properties for the interaction and detection of amyloid oligomers. In fact, any molecule that can bind amyloid aggregates could be useful for their detection.

Graphical abstract: Application of biomaterials for the detection of amyloid aggregates

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Article information


Submitted
23 Jan 2014
Accepted
17 Mar 2014
First published
15 Apr 2014

Biomater. Sci., 2014,2, 951-955
Article type
Minireview
Author version available

Application of biomaterials for the detection of amyloid aggregates

T. Zako and M. Maeda, Biomater. Sci., 2014, 2, 951
DOI: 10.1039/C4BM00026A

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